Immune Mechanisms in Neurologic Disease

Howard L. Weiner, MD
Professor of Neurology, Harvard Medical School
Co-Director, Ann Romney Center for Neurological Diseases, BWH

Howard L. Weiner is the Robert L. Kroc Professor of Neurology at the Harvard Medical School, Director and Founder of the Brigham MS Center, and Co-Director of the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital in Boston. He has pioneered immunotherapy in MS and has investigated immune mechanisms in nervous system diseases including MS, Alzheimer’s Disease, ALS, stroke, and brain tumors. He discovered Th3 regulatory T cells which act via TGF-β, now recognized as a central cytokine in immune system differentiation. He has also been at the forefront of investigations of the mucosal immune system for treatment of autoimmune and other diseases. Among many honors and awards, Dr. Weiner is the 2007 recipient of the John Dystel Prize for MS Research and in 2012 received the NIH Director’s Transformative Research Award for investigating the innate immune system in Alzheimer’s disease.