Programming Tissue-Sensing T Cells To Deliver Therapies to the Brain

Milos Simic, PhD
Cell Design Institute Fellow
University of California, San Francisco

Dr. Simic’s research focuses on combining cell engineering and synthetic biology to understand and treat brain diseases. Milos and his colleagues pioneered the concept of a programmable “tissue GPS” for cells, allowing a cell to precisely know where it is in the body to locally execute a predefined program. This concept is currently being applied for the treatment of brain cancers as well as neuroinflammation, and Milos is eager to expand this concept to treat other diseases of the brain, including neurodegeneration.

This seminar is co-sponsored by the Departments of Bioengineering and Therapeutic Sciences and Neurology.