"Dynamic Pluripotent Stem Cell States and Their Applications”

Jun Wu, PhD | Associate Professor, UT Southwestern

Join us for a trainee luncheon at noon in the IRM Pod A Conference Room, followed by Dr. Wu's seminar at 1 PM in N225. RSVP Lael.DasGupta@ucsf.edu

Dr. Wu’s work has contributed to the generation of new stem cells for basic and translational studies, and developing novel and efficient genome and epigenome editing tools. He expanded the spectrum of pluripotent states by capturing several new types of pluripotent stem cells (PSCs) with distinct molecular and phenotypic features, and helped establish a 3D culture system that supports long-term expansion of nephron progenitor cells.

Recently, he has generated PSC-derived interspecies chimeras and developed an efficient and versatile interspecies blastocyst complementation system for targeted organ-enrichment of xenogeneic donor PSCs. His group is particularly interested in harnessing interspecies chimeras for studying developmental biology in an evolutionary context, body- and organ-size determination, species’ specific behavioral traits, cancer resistance, and molecular basis of species barriers.

Sponsored by the generous support of Jonah Platt