Memory and Aging Center Grand Rounds

Reconsidering Harbingers of Alzheimer’s Disease: Risk Factors, Biomarkers, and White Matter Hyperintensities

Adam M. Brickman, PhD
Herbert Irving Associate Professor of Neuropsychology, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H. Sergievsky Center
Columbia University



Attendees will learn:

  • To review current conceptual models of Alzheimer’s disease classification and some of their caveats;
  • To discuss evidence for the involvement of white matter hyperintensities (WMH), which may be a radiological manifestation of small vessel cerebral damage, in dementia and Alzheimer’s disease;
  • To consider the extent to which WMH may interact with amyloid pathology and have a direct effect on tau-mediated neurodegeneration.



  • Planners: Lawren VandeVrede, MD, PhD; Bruce L. Miller, MD; Howard J. Rosen, MD; and Eleanor O’Brien have stated they have no relationships to disclose.
  • Speaker: Dr. Brickman will note any disclosures at the beginning of his talk.

Accreditation: The University of California, San Francisco (UCSF) School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation: UCSF designates this live activity for a maximum of 22 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The above credit is inclusive of all Memory and Aging Center Grand Rounds sessions offered January 2018 through June 2018. (1 credit per each 1-hour grand rounds session throughout the year).

NOTE: You must sign in to qualify for CME Credit

Grand Rounds presentations are for educational purposes and intended for a professional audience. This activity is not commercially supported.

Friday, August 10, 2018 at 8:00am to 9:00am

Rock Hall, Pottruck Auditorium, RH 102
1550 4th Street, San Francisco, CA 94158

Event Type

Grand Rounds


School of Medicine


Students, Postdocs, Faculty, Staff


Mission Bay


neuroscience, neurology, geriatrics


Memory and Aging Center, Department of Neurology, UCSF Weill Institute for Neurosciences


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