Keynote: Trial Designs for Implementation Science
James Hargreaves, BSc, MSc, PhD; London School of Hygiene & Tropical Health
Study Designs for Implementation Science: Optimizing What We Learn from Trials
Topics: Comparative Effectiveness, Trial Designs for Adaptive Interventions
Design of Intervention Strategies: Closing the Know/Do Gap
Topics: Community Mobilization, Network Effects, mHealthTask Shifting, Livelihood Interventions
Evaluating What Happened: Learning from Doing
Topics: Study Designs for External Validity, Seeking to ask the Big Question, Effect of Guidelines (Regression Discontinuity)
The Transport Framework: A Roadmap for External Validity
Topics: External Validity, HIV Prevention Interventions– what works where?, Bringing Context into Focus: Transportability Framework
Implementation science is an emerging field focused on closing the gap between efficacious interventions and real world practice. While the HIV research community has enthusiastically embraced the motivation for implementation science, there is far less consensus on the critical approaches to successful conduct of implementation science in the context of the HIV epidemic. Many methodological issues, which have perhaps been less emphasized in traditional clinical research, are particularly salient for knowledge about implementation. External validity is as important as internal validity. Context is a crucial. Engagement with diverse stakeholders is requisite. Managing flaws in data from electronic clinical records can render more representative data most useful. Implementation science, therefore, seeks not simply more research, but rather different research.
To advance implementation science in response to the HIV epidemic, the Center for HIV Research and the Implementation Science Working Group propose a symposium to engage experts in HIV research, implementation science, epidemiology and social science to raise and address critical issues in the conduct of implementation science during a one day symposium. Within the HIV research community, these articles will help to catalyze the next generation of implementation science to end the HIV epidemic. If successful, this conversation will both use HIV research to advance implementation science more generally, as well as bring emerging perspectives to bear on the HIV epidemic.
Friday, September 28, 2018 at 8:30am to 3:30pm
Mission Hall, 1400
550 16th St, San Francisco, CA 94158