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VERSION:2.0
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CALSCALE:GREGORIAN
X-WR-CALNAME:Stem Cell Genome Editing Series
X-WR-TIMEZONE:Pacific Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260910T130607Z
UID:tag:localist.com\,2008:EventInstance_50896746994073
DTSTART:20260127T201000Z
DTEND:20260127T210000Z
DESCRIPTION:Join us for our Stem Cell Genome Editing Series\, showcasing cu
 tting-edge advances in genome editing for stem cell biology and therapeuti
 c development. The series reflects the Center for Genome Surgery’s missi
 on to address critical challenges in gene editing and aligns with the UCSF
  Broad Stem Cell Center’s vision to Discover\, Engineer\, Heal. At our J
 an 27 session\, we will hear from speaker Nadav Ahituv\, PhD\, who will pr
 esent “Targeting gene regulatory elements for therapeutic benefits."\n\n
 By targeting regulatory elements via CRISPR activation (CRISPRa)\, we show
  that they can be used to rescue a variety of haploinsufficient diseases (
 having ~50% dosage reduction due to having only one functional allele). In
  addition\, utilizing CRISPRa to engineer adipocytes and adipose organoids
  to outcompete tumors for nutrients\, we show that they can be used as a n
 ovel cancer therapy\, termed Adipose Manipulation Transplantation (AMT).\n
 \nSpeaker Lineup\nJan 27 | Nadav Ahituv “Targeting gene regulatory eleme
 nts for therapeutic benefits”\nFeb 10 | Greg Mohl "High-throughput platf
 orms for gene editing and delivery optimization"\nFeb 24 | Serine Avagyan 
 "Multiplex mosaic CRISPR-cas9 mutagenesis in vivo"\nMarch 10 | Alex Marson
  "Decoding and Reprogramming Human T Cell Circuits with CRISPR"\nMarch 24 
 | Peter Bruno "Synthetic biology to enable antigen presentation screening 
 systems"\nApril 28 | James Gardner TBA\nMay 12 | Seth Shipman TBA\n\nUCSF 
 welcomes all participants to our events. If you need a reasonable accommod
 ation to participate in this event because of a disability\, please contac
 t IRMEvents@ucsf.edu as soon as possible.
GEO:37.761928;-122.458247
LOCATION:Ray and Dagmar Dolby Regeneration Medicine Building \, Boardroom
SUMMARY:Stem Cell Genome Editing Series
URL;VALUE=URI:https://calendar.ucsf.edu/event/genome-editing-technologies-a
 pplications-series-8070
CATEGORIES:Research & Academia
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