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Women attending antenatal care (ANC) are a generally healthy, easy-access population, contributing valuable data for infectious disease surveillance and wider health metrics at the community level. ANC-level malaria surveillance can provide a routine measure of the malaria burden in pregnancy, which countries lack, whilst potentially improving pregnancy outcomes. It can also provide contemporary information on temporal trends and the geographic distribution of malaria burden as well as intervention coverage in the population to guide resource allocation and to assess progress towards elimination. Here, we will discuss the use of malaria surveillance in pregnant women at first ANC visit for different use cases, including Stratification; Impact assessment of antimalarial interventions; Reactive surveillance; and Early warning signals of parasite-driven biological threats through genomic approaches. 

Join the EPPIcenter at UCSF in welcoming our collaborator Alfredo Mayor.

Alfredo Mayor is an Associate Research Professor at Instituto Salud Global (ISGlobal), Barcelona Center for International Health Research (CRESIB) and Manhica Health Research Center (CISM, MOZAMBIQUE), specializing in malaria parasitology. The overall goal of Dr. Mayor’s translational research is to contribute to the development of new tools for the control and eventual elimination of malaria through the understanding of key malaria physiopathology events. His research team ‘Malaria Physiopathology’ combines molecular biology, immunology and clinical medicine with innovation in multiplexed platforms to decipher the interplay between malaria transmission, parasite factors, immunity and disease. With collaborators at the Manhiça Health Research Centre (CISM; Mozambique) and the St Joseph Catholic Hospital (SJCH; Monrovia), his group has described the immunological and parasitological factors involved in the progression of malaria disease in children and pregnant women. His group is currently applying molecular and immunological techniques to understand the physiopathology of malaria in the most vulnerable populations, as well as to develop new diagnostic and surveillance tools for malaria monitoring and response in elimination contexts.

 

The EPPIcenter at UCSF aims to advance the understanding of infectious diseases to reduce global morbidity and mortality. We believe that the greatest success in the fight against infectious diseases will come through a highly interdisciplinary, systems epidemiology approach, connecting traditionally siloed theoretical work, technology development, generation and collection of empiric data, and analysis using statistical and mathematical modeling.

 

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  • Thomas Egan

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