The majority of Americans are living with pain, according to the findings from a report recently released by the National Center for Health Statistics. Pain affects more than your body, increasing stress and depression which can make pain worse, leading to a vicious cycle. While many of us experience pain, there can be significant differences in how pain is perceived due to the interplay of environment, genetics, and psychology. Despite its prevalence, massive financial burden, and widespread association with disability, the effective management of pain remains a challenge. In this six-part series taught by leading experts at UCSF, we will explore the causes, consequences, and treatment of pain as well as barriers to providing effective pain relief.