UCSF/SFVAMC Center for Population Brain Health Lecture Series

Synthesizing Data From Respondents and Proxies in Epidemiologic Survey Studies of Older Adults With Cognitive Impairment

Sei Lee, MD, MAS
Associate Professor
Dept. of Medicine, Division of Geriatrics
UCSF School of Medicine

Senior Physician Scholar
VA Quality Scholars Fellowship Program
San Francisco VA Health Care System


Epidemiologic survey studies such as the Health and Retirement Study (HRS) or the National Health and Aging Trends Study (NHATS) are a valuable resource for research focusing on older adults with cognitive impairment.  While some data elements are obtained for all participants, others are obtained for only those who can respond themselves while different data elements are only obtained from proxies.  This leads to challenges on how best to incorporate these different data elements into epidemiologic studies across the spectrum of cognitive impairment.  Using the case example of our current research, I will engage the group in a discussion regarding how best to synthesize differential respondent and proxy data in studies of older adults across the spectrum of cognitive impairment.


Sei Lee is an Associate Professor in the Division of Geriatrics and Senior Scholar for the San Francisco VA Quality Scholars fellowship. His research focuses on improving the targeting of preventive interventions in older adults to maximize benefits and minimize harms. Dr. Lee attended medical school at the University of Illinois-Rockford, then moved to UCSF where he completed Primary Care Internal Medicine residency and a Geriatric Medicine fellowship. He also completed the VA Quality Scholars fellowship, receiving advanced training in methodologies related to healthcare quality from the San Francisco VA and obtained a Master’s degree in clinical research from UCSF.

Dr. Lee joined the Division of Geriatrics faculty in 2007. Dr. Lee’s research examines how a patient’s health status can help individualize preventive and treatment decisions, with a special focus on diabetes care for frail nursing home residents. Dr. Lee is an expert in clinical prediction and has published research on predicting mortality, functional decline, dementia and pneumonia. In his clinical work, Dr. Lee supervises and trains residents, fellows and medical students while providing care for internal medicine and palliative care patients at the San Francisco Veterans Affairs Medical Center.

Thursday, February 14 at 10:00am to 11:30am

SF VA Medical Center, Building 11 Conference Room (located in basement)
4150 Clement Street, San Francisco, CA 94121

Event Type

Lecture/Seminar, Academic


School of Medicine


Students, Postdocs, Faculty


SF VA Medical Center



Department of Psychiatry, UCSF Weill Institute for Neurosciences
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